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Urology

Tamstone-D®

Tamsulosin HCl + Dutasteride
0.4 mg + 0.5 mg capsulesPack of 20Once dailyRx only

Tamsulosin 0.4 mg + dutasteride 0.5 mg — fixed-dose dual therapy for benign prostatic hyperplasia, one capsule once daily.

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Tamstone-D® carton
Product overview

Dual action for benign prostatic hyperplasia

Tamstone-D® combines tamsulosin HCl 0.4 mg and dutasteride 0.5 mg in one capsule, addressing both the functional and the structural mechanisms of BPH in a single daily dose.

Faster improvement in LUTS

Functional relief from the alpha-blocker within days.

Disease modification

Sustained reduction in prostate volume from 5α-reductase inhibition.

Once daily

One capsule once daily.

Mechanism of action

Two mechanisms, one capsule

Tamsulosin 0.4 mg · functional reliefDutasteride 0.5 mg · disease modification Relaxes prostate & bladder-necksmooth muscle → better urinary flowSuppresses DHT (>90%) →gradual reduction in prostate volume
Schematic, not to scale. Adapted from the Salventis Tamstone-D® literature (“Mechanistic synergy”).

Tamsulosin HCl 0.4 mg

  • Selective α1A-adrenoceptor antagonist
  • Relaxes prostate and bladder-neck smooth muscle
  • Improves urinary flow (Qmax)

Dutasteride 0.5 mg

  • Dual type I and type II 5α-reductase inhibitor
  • Suppresses conversion of testosterone to DHT (>90%)
  • Reduces prostate volume
Prescribing essentials

Benefits & dosing

Core benefits reported in Salventis literature

  • Relief from BPH symptoms
  • Improves urine flow and bladder emptying
  • Reduces frequency and nocturia
  • Supports prostate size reduction
  • Decreased risk of acute urinary retention and BPH-related surgery

Indication

Benign prostatic hyperplasia.

Dosage

One capsule once daily.

Composition

Each hard gelatin capsule contains dutasteride 0.5 mg (as soft gelatin capsule) and tamsulosin hydrochloride 0.4 mg (as modified-release pellets).

Dosage & administration

One capsule once daily.

Storage

As stated on the carton. Keep out of reach of children.

Safety & precautions

Contraindications, warnings and adverse reactions are set out in the approved prescribing information, available to healthcare professionals on request.

Composition & presentation

Product information

BrandTamstone-D®
GenericTamsulosin HCl + dutasteride
StrengthTamsulosin HCl 0.4 mg + dutasteride 0.5 mg per capsule
Dosage formHard gelatin capsule (modified-release pellets + soft gelatin capsule)
Pack20 capsules
Therapeutic areaUrology
Prescription statusPrescription-only medicine
ManufacturerBiogen Life Sciences, Rawalpindi
DRAP registration no.Available on request
Marketed bySalventis Pharma SMC (Pvt.) Ltd., Islamabad
Resources

Prescribing information

PI
Full prescribing information — Tamstone-D®Provided to healthcare professionals on request by Salventis Pharma.
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For healthcare professionals. All Salventis products are prescription-only medicines, to be sold on the prescription of a registered medical practitioner. Information on this site summarises the approved prescribing information and supplied product literature; it is not a substitute for the full prescribing information, which is available on request from Salventis Pharma. To report a suspected adverse reaction, contact info@salventispharma.com.